Name: 
 

AP CH13


Multiple Choice
Identify the letter of the choice that best completes the statement or answers the question.
 

1. 
Friedrich Miescher is credited with
a.
proposing DNA as the hereditary material.
b.
finding a cure for pneumonia.
c.
telling us that A=T and G=C.
d.
discovering nucleic acids.
 

2. 
Bacteriophages are
a.
large bacteria.
b.
pathogens (disease-producing bacteria).
c.
viruses.
d.
cellular components.
e.
protistans.
 

3. 
The significance of the experiments in which 32P and 35S were used is that
a.
the semiconservative nature of DNA replication was finally demonstrated.
b.
it demonstrated that harmless bacterial cells had become permanently transformed through a change in the bacterial hereditary system.
c.
it established that pure DNA extracted from disease-causing bacteria transformed harmless strains into killer strains.
d.
it demonstrated that radioactively labeled bacteriophages transfer their DNA but not their protein coats to their host bacteria.
e.
none of these
 

4. 
The experiments of which of the following researchers clearly distinguished DNA as the hereditary material (as opposed to protein)?
a.
Pauling
b.
Hershey and Chase
c.
Griffith
d.
Watson and Crick
e.
Avery
 

5. 
Sulfur is
a.
found in proteins, but not nucleic acids.
b.
a vital component of .
c.
found in nucleic acids, but not proteins.
d.
needed for bacteriophages to attach to bacteria.
e.
needed for the enzyme that splits the wall of bacteria.
 

6. 
A nucleotide may contain
a.
a purine.
b.
a pentose.
c.
a phosphate group.
d.
a pyrimidine.
e.
all of these
 

7. 
Which scientist(s) discovered the basis for the base-pair rule, which states that the amounts of adenine and thymine match, as do the amounts of cytosine and guanine?
a.
Avery
b.
Griffith
c.
Chargaff
d.
Hershey and Chase
e.
Pauling
 

8. 
From x-ray diffraction data, which of the following was determined about DNA?
a.
The molecule had uniform diameter.
b.
The molecule was long and narrow.
c.
Part of the molecule repeated itself often.
d.
The shape of the molecule could be spiral.
e.
all of these
 

9. 
In the bonding of two nucleotides,
a.
hydrogen bonds are used.
b.
adenine and thymine bind together.
c.
purines bind with pyrimidines.
d.
double-ring nitrogenous bases connect to single-ring bases.
e.
all of these
 

10. 
Adenine and guanine are
a.
double-ringed purines.
b.
single-ringed purines.
c.
double-ringed pyrimidines.
d.
single-ringed pyrimidines.
e.
amino acids.
 

11. 
Who among the following was NOT involved in working out the structure of DNA?
a.
Avery
b.
Watson
c.
Wilkins
d.
Franklin
e.
Chargaff
 

12. 
The appropriate adjective to describe DNA replication is
a.
nondisruptive.
b.
semiconservative.
c.
progressive.
d.
natural.
e.
lytic.
 

13. 
Replication of DNA
a.
produces RNA molecules.
b.
produces only new DNA.
c.
produces two molecules, each of which is half-new and half-old DNA joined lengthwise to each other.
d.
generates excessive DNA, which eventually causes the nucleus to divide.
e.
is too complex to characterize.
 

14. 
After three replications of a single DNA molecule, what percent of the resulting double helices contain one strand of the "original" DNA?
a.
0 percent
b.
25 percent
c.
50 percent
d.
75 percent
e.
100 percent
 

15. 
DNA polymerase
a.
is an enzyme.
b.
adds new nucleotides to a strand.
c.
proofreads DNA strands to see that they are correct.
d.
derives energy from ATP for synthesis of DNA strands.
e.
all of these
 

Short Answer
 
 
Five Nucleotides

Answer the following questions in reference to the five nucleotides listed below:
a.      guanine
b.      cytosine
c.      pyrimidine
d.      thymine
e.      uracil
 

16. 
Refer to Five Nucleotides. This nucleotide is not incorporated into the structure of the DNA helix.
 

17. 
Refer to Five Nucleotides. This nucleotide is a double-ringed molecule.
 

18. 
Refer to Five Nucleotides. Two hydrogen bonds connect adenine to __________ in the DNA molecule.
 



 
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